and the will take the field on Friday at Wrigley Field against , who is projected to start for the . First pitch will be at 2:20 PM ET. The Cubs are -114 moneyline favorites for this matchup against the Cardinals (-105). Chicago is a 1.5-run favorite (at +180 odds). The over/under for the game is set at 8 runs. Check out everything you need to know from a betting perspective on the Cubs-Cardinals game, regarding the run line, moneyline and total, plus expert picks. Cardinals vs. Cubs Highlights | MLB Cubs vs. Cardinals Game Information & Odds When: Friday, August 2, 2024 at 2:20 PM ET Where: Wrigley Field in Chicago, Illinois How to Watch on TV: MLB Network Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Cubs -114 -105 8 -105 -115 -1.5 +180 -218 Cubs vs. Cardinals Prediction Score Prediction: Cubs 5 George Mikan Jersey , Cardinals 4 Total Prediction: Under 8 runs Win Probabilities: Cubs 54%, Cardinals 46% Cubs vs. Cardinals Betting Insights The Cubs have won 22, or 46.8%, of the 47 games they've played as favorites this season. Chicago has a record of 20-23 in games when sportsbooks favor them by at least -114 on the moneyline. Sportsbooks have implied with the moneyline set for this matchup that the Cubs have a 53.3% chance to win. The Cardinals have been chosen as underdogs in 53 games this year and have walked away with the win 26 times (49.1%) in those games. This season, St. Louis has come away with a win 25 times in 51 chances when named as an underdog of at least -105 or longer on the moneyline. The Cardinals have an implied victory probability of 51.2% according to the moneyline set by oddsmakers for this matchup. Check out the best moments between the St. Louis Cardinals and the Chicago Cubs on Thursday, August 1. FOX Sports created this story using technology provided by and data from Sportradar. Want great stories delivered right to your inbox? FOLLOW Follow your favorites to personalize your FOX Sports experience Chicago Cubs St. Louis Cardinals Talen Horton-Tucker Jersey