When it comes to making money efficiently in Grand Theft Auto V, not all missions are created equal. Whether you're grinding to upgrade properties or just trying to squeeze more cash out of your play sessions, knowing which missions provide the highest return on investment (ROI) can help you maximize both your time and profit. This list breaks down 14 of the most lucrative missions in GTA 5—missions that balance strong payouts with short completion times, giving you the best bang for your buck.

For players using optimized GTA 5 accounts or looking to buy GTA 5 accounts that already have key mission progress unlocked, this guide is especially useful. These accounts can help you jump straight into the action without wasting time on setup.

1. Rooftop Rumble

A long-time favorite for a reason. This mission takes place in West Vinewood and is easy to complete with high-powered weapons or an armored vehicle. Its payout remains competitive despite newer updates.

2. Diamonds for Trevor

Part of the “Trevor’s Missions” set, this job offers quick cash and is great for solo players who don’t want to rely on a crew. Fast, repeatable, and low-risk.

3. Trash Talk

Unlocks at Rank 81, and it’s worth the wait. With a solid team and some coordination, you can finish this mission quickly while earning a nice chunk of change.

4. The Pacific Standard Heist (Finale)

Although it requires setup and a team, the payout from this heist remains one of the highest in the game. Efficient crews can complete it in under 15 minutes for a huge profit split.

5. Time to Get Away

One of the more underrated contact missions. Easy to solo and relatively short, especially with a fast car. The reward isn’t sky-high, but the time-to-profit ratio is excellent.

6. Series A - Coke

Part of the Series A heist lineup, this mission hits the sweet spot of being both intense and rewarding. Solid choice for players who enjoy a bit of chaos with their profits.

7. Hostile Takeover (CEO Work)

This Free Mode mission is popular among players with a good Oppressor Mk II or Buzzard. Quick, accessible, and scalable with a CEO organization.

8. Sightseer (VIP Work)

A classic for solo players. All you need is a buzzard or fast vehicle, and you're good to go. Easy money with minimal setup and downtime.

9. Judging the Jury

High payout, high fun. You’ll eliminate multiple targets across the map, and the mission scales well with an experienced crew.

10. Blow Up II

Short and explosive. If you like missions where you can cause mayhem and walk away richer, this one’s for you. Great for solo play too.

11. Dispatch Missions

These offer quick payouts and low time commitment. They’re also among the easier missions to repeat, making them ideal for casual grinding.

12. Doomsday Heist - Act I: The Data Breaches

Even though the setups take time, the finale is one of the smoothest in the Doomsday series. When done efficiently, the ROI is quite solid.

13. Headhunter (VIP Work)

Another Free Mode favorite. Perfect for players with upgraded GTA 5 accounts who want steady income between larger heists. Simple, effective, and always available.

14. Gerald’s Last Play – Make Ends Meat

Added in later updates, this contact mission is newer but surprisingly rewarding. It’s a strong pick for those looking to diversify from older mission rotations.

Whether you're running these missions on your main profile or using one of the buy GTA 5 accounts options available through services like U4N, having access to key tools—vehicles, weapon loadouts, and mission progress—can significantly boost your efficiency. Time is money in Los Santos, and these 14 missions prove that with the right strategy, both can be on your side.